Type-I IFNs in EAE drive synaptic transcriptional responses in neurons and astrocytes in the brain
Shane M. O’Neil, Hyunjung Min, Li Xu, Anthony J. Filiano
This study identifies the role of type-I IFNs in driving synaptic and metabolic transcriptional responses in neurons and astrocytes during EAE, independent of the spinal cord.
bioRxiv · Sep 25, 2026 · PreprintNeuroscience