Synergism and antagonism of two distinct, but confused, Nrf1 factors in integral regulation of the nuclear-to mitochondrial respiratory and antioxidant transcription networks
Shuwei Zhang, Yangxu Deng, Yuancai Xiang, Shaofan Hu, Lu Qiu, Yiguo Zhang
The paper identifies synergistic and antagonistic roles of Nfe2l1 and Nfe2l2 in regulating -PalNRF1 and TFAM expression, with species-specific differences observed between mice and humans.
Oxidative Medicine and Cellular Longevity · Nov 16, 2020Peer-reviewedMolecular Biology