Distant homologies and domain conservation of the Hereditary Spastic Paraplegia protein SPG11/ALS5/spatacsin
Alexander Patto, Cahir J. O’Kane
The paper identifies conserved regions of the SPG11 protein and their potential functions in intracellular trafficking, linking them to disease mechanisms in hereditary spastic paraplegia and Charcot-Marie-Tooth neuropathy.
bioRxiv · Mar 8, 2020 · PreprintNeuroscience