Reference-free cell-type deconvolution of multi-cellular pixel-resolution spatially resolved transcriptomics data
Brendan F. Miller, Feiyang Huang, Lyla Atta, Arpan Sahoo, Jean Fan
This paper introduces STdeconvolve, a reference-free method for cell-type deconvolution of spatially resolved transcriptomics data at multi-cellular pixel resolution, showing effective recovery of cell-type profiles without external references.
Nature Communications · Apr 29, 2022Peer-reviewedBioinformatics