Author

Sahar Aghakhani

Centre Inria de SaclayORCID 0000-0002-6392-4687Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Systems Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Research Focus:differential expression· 1 Assay:metabolomics· 1 Approach:simulation· 1

Frequent Co-Authors

Anna NiarakisiD· 2 shared Sylvain SolimaniD· 2 shared Sacha E Silva-SaffariD· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersSystems Biology

Anna NiarakisORCID

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2 papers

Recent·Most cited

Hybrid computational modeling highlights reverse Warburg effect in breast cancer-associated fibroblasts

Sahar Aghakhani, Sacha E Silva-Saffar, Sylvain Soliman, Anna Niarakis

This paper develops a hybrid computational model of breast cancer-associated fibroblasts to identify HIF-1 as a driver of the reverse Warburg effect.

Computational and Structural Biotechnology Journal · Jan 1, 2023Peer-reviewedSystems Biology

Metabolic Reprogramming in Rheumatoid Arthritis Synovial Fibroblasts: a Hybrid Modeling Approach

Sahar Aghakhani, Sylvain Soliman, Anna Niarakis

This paper develops a hybrid model of RASFs integrating signaling, gene regulation, and metabolism to simulate metabolic reprogramming and hypothesize a reverse Warburg effect in RA.

PLoS Computational Biology · Dec 12, 2022Peer-reviewedSystems Biology