Benchmarking ambient RNA removal across droplet and well-plate platforms reveals artificial count generation as a critical failure mode of scAR and CellClear
Lukas Schroeder, Susanne Gerber, Nicolas Ruffini
The paper benchmarks ambient RNA removal tools across different platforms, finding that scAR and CellClear generate artificial counts and cell types, while CellBender and SoupX perform reliably.
bioRxiv · Apr 10, 2026 · PreprintBioinformatics