Kimberly E. Roche

Social and environmental predictors of gut microbiome age in wild baboons

The paper develops a microbiome-based age predictor for wild baboons using 13,563 gut microbial profiles and finds that microbiome age reflects current social and environmental conditions but not developmental milestones or lifespan.

The accuracy of absolute differential abundance analysis from relative count data

This study evaluates the accuracy of differential abundance analysis using renormalized relative count data compared to absolute abundances, finding high consistency but potential for increased false positives under widespread abundance changes.

Naught all zeros in sequence count data are the same

The paper evaluates zero-handling models in genomic and microbiome data, showing significant disagreement in identifying differentially expressed sequences and finding simple count models sufficient across processes.