How Top-Down and Bottom-Up Regulation in Fronto-Amygdalar Network Changes over Time during Drug Cue-Exposure: An fMRI Study among Abstinent Heroin User
Arash Zare Sadeghi, Mohammad Ali Oghabian, Mehran Zare-Bidoky, Seyed Amir Hossein Batouli, Hamed Ekhtiari
This study uses fMRI and Dynamic Causal Modelling to examine how top-down regulation in the fronto-amygdalar network changes over time during drug cue-exposure in abstinent heroin users, finding increased amygdala input and decreased DLPFC modulation.
bioRxiv · Aug 5, 2019 · PreprintNeuroscience