Histone acetylation insulator SET orchestrates PP2A inhibition and super-enhancer activation
Xu He, Di Wu, Jin Xu, Yubin Lei, Yalan Lei, Xianjun Yu, Si Shi
The paper identifies SET as a factor that disrupts PP2A activity and acts as a histone acetylation insulator to promote transcription of super-enhancer-associated genes in pancreatic cancer cells.
bioRxiv · Jan 15, 2023 · PreprintMolecular Biology