The rare DRB1*04-DQ8 haplotype is the main discriminative HLA class II genetic driver of Early-Onset Type 1 Diabetes in the Portuguese population
Íris Caramalho, Paula Matoso, Dário Ligeiro, Tiago Paixão, Daniel Sobral, Ana Laura Fitas, Catarina Limbert, Jocelyne Demengeot, Carlos Penha‐Gonçalves
The paper identifies the rare DRB1*04:08-DQ8 haplotype as a major genetic driver of Early-Onset Type 1 Diabetes in the Portuguese population.
medRxiv · Jul 23, 2023 · PreprintGenetic & Genomic Medicine