MODEL BASED OPTIMIZATION OF THE TERPENOIDS BIOSYNTHESIS IN E. coli
Fernando Alvarez‐Vasquez, Carlos María Gonzalez-Alcon, Julia Gallego‐Jara, Teresa de Diego Puente, Manuel Cánovas, Néstor Vicente Torres
The paper optimizes terpenoids biosynthesis in E. coli by modifying enzyme kcat values and combining them with other strategies to achieve a 21.22 fold increase in biosynthetic flux.
bioRxiv · Aug 11, 2021 · PreprintSystems Biology