Protein interaction kinetics delimit the performance of phosphorylation-driven protein switches.
Daniel L. Winter, Adelgisa R. Wairara, Jack L. Bennett, William A. Donald, Dominic J. Glover
This study develops a theoretical framework to evaluate phosphorylation-driven protein switches and demonstrates two novel switches with fast, reversible responses to kinase activity.
ACS Synthetic Biology · Jun 3, 2024Peer-reviewedSynthetic Biology