Accounting for Cellular-Level Variation in Lysis: Implications for Virus-Host Dynamics
Marian Dominguez-Mirazo, Jeremy D. Harris, David Demory, Joshua S. Weitz
This paper shows that one-step growth curves underestimate the mean latent period of bacteriophages due to cellular-level variability in lysis timing, and proposes a computational framework to correct this bias.
mBio · Jul 19, 2024Peer-reviewedEcology