Efficient Representations of Tumor Diversity with Paired DNA-RNA Aberrations
Qian Ke, Wikum Dinalankara, Laurent Younes B, Donald Geman, Luigi Marchionni
The paper introduces a method to represent tumor diversity using paired DNA-RNA aberrations, identifies minimal coverings of aberrant gene pairs, and quantifies heterogeneity through entropy measures across cancer types.
PLoS Computational Biology · Jun 11, 2021Peer-reviewedGenomics