Author

Lernik S. Hunanyan

Russian-Armenian UniversityORCID 0000-0002-6913-0175Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 2 Approach:machine learning (classical)· 1 Assay:protein structure· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Hovakim GrabskiiD· 2 shared Hrachik R. Vardapetyan· 2 shared Susanna G. TiratsuyaniD· 2 shared

Activity by Year

2017-2019 · peak 1/yr

Co-Author Collaboration Network

3 top collaborators · 3 mutual co-author links

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2 shared papersBioinformatics

Hovakim GrabskiORCID

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2 papers

Recent·Most cited

Interaction of N-3-oxododecanoyl homoserine lactone with transcriptional regulator LasR of Pseudomonas aeruginosa: Insights from molecular docking and dynamics simulations

Hovakim Grabski, Lernik S. Hunanyan, Susanna G. Tiratsuyan, Hrachik R. Vardapetyan

The paper analyzes the molecular interactions of the autoinducer 3-0-C12-HSL with the LasR protein of Pseudomonas aeruginosa using docking and dynamics simulations, identifying a new interaction site and dimerization form.

F1000Research · Mar 22, 2019Peer-reviewedBioinformatics

Interaction of quercetin with transcriptional regulator LasR of Pseudomonas aeruginosa: Mechanistic insights of the inhibition of virulence through quorum sensing

Hovakim Grabski, Lernik S. Hunanyan, Susanna G. Tiratsuyan, Hrachik R. Vardapetyan

This study investigates how quercetin interacts with LasR, a transcriptional regulator in Pseudomonas aeruginosa, to inhibit quorum sensing and biofilm formation through two distinct binding modes.

bioRxiv · Dec 27, 2017 · PreprintBioinformatics