Plate design confounds donor variation and model evaluation in single-cell perturbation screens
Ghazal Ghajari, Krishnaprasad Thirunarayan, Fathi Amsaad
The paper shows that plate design confounds donor variation in single-cell perturbation screens and demonstrates how improved analysis methods can change interpretations of recent studies.
bioRxiv · Nov 6, 2026 · PreprintBioinformatics