Author

Derek Setter

University of EdinburghORCID 0000-0002-7101-443XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:benchmarking· 2 Research Focus:variant calling· 2 Assay:whole-genome sequencing· 2 Research Focus:database / resource· 1 Approach:deep learning· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

Konrad LohseiD· 2 shared Abdelmajid OmarjeeiD· 1 shared Alexander MackintoshiD· 1 shared Gertjan BisschopiD· 1 shared Hossameldin LoayiD· 1 shared Jerome KelleheriD· 1 shared Stuart J. E. BairdiD· 1 shared

Activity by Year

2024-2026 · peak 2/yr

Co-Author Collaboration Network

7 top collaborators · 11 mutual co-author links

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2 shared papersGenomics

Konrad LohseORCID

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3 papers

Recent·Most cited

Tuning the SMC: efficient simulation and the structure of ARGs

Hossameldin Loay, Gertjan Bisschop, Derek Setter, Abdelmajid Omarjee, Jerome Kelleher, Konrad Lohse

This paper introduces SMC(k), a tunable approximation of the Coalescent with Recombination, showing it balances computational efficiency and accuracy in simulating Ancestral Recombination Graphs.

bioRxiv · Sep 4, 2026 · PreprintGenomics

diempy: fast and reference-free genome polarisation

Derek Setter, Konrad Lohse, Stuart J. E. Baird

diempy provides a fast, reference-free method for genome polarisation, enabling analysis of population structure and admixture without pure reference panels.

bioRxiv · Mar 10, 2026 · PreprintEvolutionary Biology

Genealogical asymmetry under the IM model and a two-taxon test for gene flow

Alexander Mackintosh, Derek Setter

This paper introduces a new statistic, Am, to detect gene flow between populations using genealogical asymmetry under the isolation-migration model, validated with simulations and applied to Heliconius butterflies and Odocoileus deer.

Genetics · Sep 30, 2024Peer-reviewedEvolutionary Biology