Peptide generative design with weakly order-dependent autoregressive language model and lifelong learning
Zhiwei Nie, Daixi Li, Yutian Liu, Fan Xu, Hongyu Zhang, Xiansong Huang, Xudong Liu, Zhennan Wang, Yiming Ma, Yuxin Ye, Feng Yin, Wen-Bin Zhang, Zhixiang Ren, Zhihong Liu, Zigang Li, Jie Chen
This paper introduces PepGenWOA, a generative model for bioactive peptide design that outperforms existing methods and enables efficient virtual screening.
bioRxiv · Dec 31, 2023 · PreprintBioinformatics