SpaCCC: Large language model-based cell-cell communication inference for spatially resolved transcriptomic data
Boya Ji, Xiaoqi Wang, Debin Qiao, Liwen Xu, Shaoliang Peng
SpaCCC uses a fine-tuned LLM and gene network to infer cell-cell communications from spatial transcriptomic data, outperforming existing methods and revealing hidden ligand-receptor pairs.
Big Data Mining and Analytics · Dec 1, 2024Peer-reviewedBioinformatics