Modeling cross-regulatory influences on monolignol transcripts and proteins under single and combinatorial gene knockdowns in Populus trichocarpa
Megan L. Matthews, Jack P. Wang, Ronald R. Sederoff, Vincent L. Chiang, Cranos Williams
The paper develops a computational model to estimate monolignol transcript and protein abundances under gene knockdowns, showing improved accuracy in predicting responses to single and combinatorial perturbations.
PLoS Computational Biology · Apr 10, 2020Peer-reviewedSystems Biology