CyclicBoltz1, fast and accurately predicting structures of cyclic peptides and complexes containing non-canonical amino acids using AlphaFold 3 Framework
Xuezhi Xie, Christina Z Li, Jin Sub Lee, Philip M. Kim
The paper extends the AlphaFold3 framework to predict structures of cyclic peptides with non-canonical amino acids, outperforming existing models on a test set.
bioRxiv · Feb 11, 2025 · PreprintBioinformatics