Mendelian Randomization analyses reveal a causal effect of thyroid function on stroke via atrial fibrillation
Eirini Marouli, Aleksander Kuś, Fabiola Del Greco M, Layal Chaker, Robin Patrick Peeters, Alexander Teumer, Panos Deloukas, Marco Medici
This paper uses Mendelian Randomization to show that normal-range TSH levels and Hashimoto's Disease causally affect stroke and CAD risk, mediated through atrial fibrillation and BMI respectively.
bioRxiv · Jul 30, 2019 · PreprintGenetics