Impact of single-cell RNA reference selection for the deconvolution of breast cancer spatial transcriptomics datasets
Stefan Altendorfer, Scott James Walker, Carsten Oliver Daub
This study evaluates how reference selection affects deconvolution accuracy in breast cancer spatial transcriptomics datasets, finding that small references can be effective and that perfect reference-ST matching improves results.
International Journal of Cancer · Sep 8, 2026Peer-reviewedBioinformatics