Identifying endogenous peptide receptors bycombining structure and transmembrane topologyprediction
Felix Teufel, Jan C. Refsgaard, Marina A. Kasimova, Christian T. Madsen, Carsten Stahlhut, Mads Grønborg, Ole Winther, Dennis Madsen
The paper uses AlphaFold-Multimer and DeepTMHMM to identify cognate receptors for secreted endogenous peptides by prioritizing interactions with high confidence metrics and filtering biologically implausible ones.
bioRxiv · Oct 28, 2022 · PreprintBioinformatics