Deciphering the association of spatial landscapes of DCIS with recurrence as invasive breast cancer
Nicola Graham, Arran Turnbull, Carlos Martínez‐Pérez, J. Michael Dixon, Florent Petitprez, Takanori Kitamura
This study uses spatial transcriptomics to identify stromal cell gradients in DCIS associated with recurrence as invasive breast cancer, highlighting TREM2+ macrophages and their interactions with epithelial cells.
bioRxiv · Sep 28, 2026 · PreprintCancer Biology