Pathogenic IgG from long COVID patients with neurological sequelae triggers sensitive but not cognitive impairments upon transfer into mice
Margaux Mignolet, Catherine Deroux, Thomas Florkin, Valéry Bielarz, Kathleen De Swert, Nicolas Halloin, Lindsay Sprimont, Aurélie Ladang, Fabienne George, Jacques Gilloteaux, Laurence Abeloos, Pierre Garin, Johan Van Weyenbergh, Marc Jamoulle, Claire Diederich, , Charles Nicaise
The paper investigates whether IgG from long COVID patients with neurological symptoms can induce pain-related symptoms in mice, finding that they bind to sensory neurons and cause transient mechanical allodynia.
Acta Neuropathologica · Apr 29, 2026Peer-reviewedNeuroscience