Author

Lane Guolan Chen

The University of Hong KongORCID 0000-0002-7761-2334Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:gene regulatory network inference· 2 Assay:GWAS summary statistics· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Pak Chung ShamiD· 2 shared

Activity by Year

2026-2026 · peak 2/yr

2 papers

Recent·Most cited

GeneticsbioRxivPreprintNov 4, 2026

LRCQ: phenome-wide heritability enrichment of genomic loci from GWAS summary statistics

Lane Guolan Chen, Pak Chung Sham

LRCQ estimates phenome-wide heritability enrichment of genomic loci using GWAS summary statistics, identifying enriched regions and their functional annotations.

DOI 10.64898/2026.11.02.763731

humanGWAS summary statistics

GeneticsbioRxivPreprintNov 4, 2026

LRCP: identifying functionally related SNPs and genes from phenome-wide genetic-effect correlations using GWAS summary statistics

Lane Guolan Chen, Pak Chung Sham

LRCP identifies functionally related SNPs and genes by estimating phenome-wide genetic-effect correlations from GWAS summary statistics, improving accuracy over naive methods.

DOI 10.64898/2026.11.02.763742

humanGWAS summary statistics