Senataxin modulates resistance to cisplatin through an R-loop mediated mechanism in HPV-associated Head and Neck Squamous Cell Carcinoma
Hannah L. Crane, Ian Carr, Keith David Hunter, Sherif F. El‐Khamisy
This study shows that senataxin modulates cisplatin resistance in HPV-associated head and neck cancer through R-loop regulation, with higher R-loop burden in HPV+ tumors and metastases.
bioRxiv · Feb 22, 2024 · PreprintMolecular Biology