Jim Karagiannis

A geometric representation of gene-by-gene and gene-by-environment interactions on the extended complex plane

The paper introduces a geometric framework on the extended complex plane to quantify gene-by-gene and gene-by-environment interactions using complex transformations and buffering concepts.

A Mathematical Framework for the Quantitative Analysis of Genetic Buffering

This paper introduces a mathematical framework to classify, quantify, and compare genetic buffering relationships between genes using a ratio scale and a novel 'parallel' model.