Biopsy-aware phylogenetic reconstruction from longitudinal single-cell copy number profiles
Jarosław Paszek, Agnieszka Mykowiecka, Krzysztof Gogolewski
This paper introduces biopsy-guided methods for phylogenetic reconstruction from longitudinal single-cell copy number profiles, showing improved accuracy over pooled methods in simulated data and demonstrating feasibility in patient-derived data.
bioRxiv · Oct 16, 2026 · PreprintBioinformatics