An improved model for prediction of de novo designed proteins with diverse geometries
Benjamin Orr, Stephanie E. Crilly, Deniz Akpinaroglu, Eleanor Zhu, Michael J. Keiser, Tanja Kortemme
The paper presents a fine-tuned Alphafold2 model that better captures geometric diversity in de novo designed proteins compared to standard methods.
bioRxiv · Jun 2, 2025 · PreprintBioinformatics