Author

William Boulton

University of East AngliaORCID 0000-0002-8258-4673Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Assay:metagenomics· 2 Approach:simulation· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1 Research Focus:ecology & biodiversity· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

Nick GoldmaniD· 2 shared Nicola De MaioiD· 2 shared Conor R. WalkeriD· 1 shared Elizabeth J. ConnorsiD· 1 shared Emelia J. ChamberlainiD· 1 shared Fatma Rabia FidaniD· 1 shared Heather H Kim· 1 shared Hubert DeniseiD· 1 shared

Activity by Year

2022-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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2 shared papersBioinformatics

Nick GoldmanORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

From microbial diversity to function; evaluating dimensionality reduction methods

Emelia J. Chamberlain, William Boulton, Elizabeth J. Connors, Theodore Calianos, Jeff S. Bowman, Jessie M. Creamean, Thomas Möck, Heather H Kim

The paper evaluates dimensionality reduction methods for microbial oceanography data, finding that Self Organizing Maps (SOM) better identify functionally distinct microbial ecotypes than Principal Coordinate Analysis (PCoA).

bioRxiv · Oct 30, 2025 · PreprintEcology

SWAMPy: Simulating SARS-CoV-2 Wastewater Amplicon Metagenomes with Python

William Boulton, Fatma Rabia Fidan, Hubert Denise, Nicola De Maio, Nick Goldman

SWAMPy generates realistic SARS-CoV-2 wastewater amplicon metagenomes to test and improve analysis methods.

bioRxiv · Dec 10, 2022 · PreprintBioinformatics

phastSim: efficient simulation of sequence evolution for pandemic-scale datasets

Nicola De Maio, William Boulton, Lukas Weilguny, Conor R. Walker, Yatish Turakhia, Russell B Corbett-Detig, Nick Goldman

The paper introduces phastSim, a tool for efficiently simulating sequence evolution on large phylogenetic trees, particularly for SARS-CoV-2-like datasets.

PLoS Computational Biology · Apr 29, 2022Peer-reviewedBioinformatics