Robust Identification of Drug Mechanism of Action Associated Genes Across Heterogeneous Drug Treated Datasets
Mahfuza Sharmin, Maliha Aziz, Ewy A. Mathé
This paper introduces ConcuRx, a statistical framework that improves gene prioritization across heterogeneous CRISPR drug-response datasets by modeling between-study variability, leading to better identification of MOA-associated genes.
bioRxiv · Oct 21, 2026 · PreprintBioinformatics