Benchmarking AI Models for In Silico Gene Perturbation of Cells
Chen Li, Haoxiang Gao, Yuli She, Haiyang Bian, Qing Chen, Kai Liu, Lei Wei, Xuegong Zhang
This study benchmarks 10 in silico gene perturbation methods across four scenarios, identifying strengths and limitations in predicting perturbation effects and zero-shot transfer.
bioRxiv · Dec 20, 2024 · PreprintBioinformatics