An application of the MR-Horse method to reduce selection bias in genome-wide association studies of disease progression
Killian Donovan, Jason Torres, Doreen Zhu, William Guy Herrington, Natalie Staplin
The paper applies the MR-Horse method to reduce selection bias in GWAS of disease progression by accounting for genetic correlation and pleiotropy, showing reduced bias and controlled type 1 error rates.
European Journal of Human Genetics · Jun 3, 2025Peer-reviewedGenetics