Large-Scale Assessment of Animal-to-Human Drug Translation Using Natural Language Processing
Simona Emilova Doneva, Tilia Ellendorff, Gerold Schneider, Leonhard Held, Viktor von Wyl, T. Ian Simpson, Beate Sick, Benjamin Victor Ineichen
This paper uses NLP to analyze 500,000 animal drug studies and links them to clinical data, finding that only 3.1% reach regulatory approval and that species diversity and blinding improve translation success.
bioRxiv · May 22, 2026 · PreprintBioinformatics