Integrating Alternative Fragmentation Techniques into Standard LC-MS Workflows Using a Single Deep Learning Model Enhances Proteome Coverage
Nikita Levin, Cemil Can Saylan, Joel Lapin, Yana Demyanenko, Kevin Yang, John D. Sidda, Alexey I. Nesvizhskii, Mathias Wilhelm, Shabaz Mohammed
The paper develops a deep learning model that integrates multiple fragmentation techniques into standard LC-MS workflows, improving proteome coverage and identification rates.
bioRxiv · May 28, 2025 · PreprintSystems Biology