Author

Xizhe Zhang

City Of Hope National Medical CenterORCID 0000-0002-8684-4591Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 2

Signature Assays, Organisms & Methods

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Approach:statistical model· 2 Research Focus:gene regulatory network inference· 1 Assay:Hi-C· 1 Organism:human· 1

Frequent Co-Authors

Baojun Wei· 1 shared Chunyu PaniD· 1 shared Grigoriy GogoshiniD· 1 shared Jieping Yang· 1 shared Jun An· 1 shared Meng YuiD· 1 shared Sergio BranciamoreiD· 1 shared Shuangjie LiuiD· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperBioinformatics

Baojun Wei

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2 papers

Recent·Most cited

Cancer-keeping genes as therapeutic targets

Xizhe Zhang, Chunyu Pan, Xinru Wei, Meng Yu, Shuangjie Liu, Jun An, Jieping Yang, Baojun Wei, Wenjun Hao, Yang Yao, Yuyan Zhu, Weixiong Zhang

The paper identifies cancer-keeping genes (CKGs) as therapeutic targets by extending network structural controllability theory to bladder cancer and validates their cancer-suppressing effects through experiments.

bioRxiv · Jun 13, 2022 · PreprintBioinformatics

Characterization of DNA extrusion scenarios underlying aggregate Hi-C patterns by a new computational framework

Xizhe Zhang, Grigoriy Gogoshin, Sergio Branciamore

The paper introduces a computational framework to reconstruct DNA extrusion scenarios from aggregate Hi-C data and demonstrates how DNA extrusion explains directional biases and dynamic promoter-enhancer interactions.

bioRxiv · Jun 28, 2021 · PreprintBioinformatics