Downregulation of O-GlcNAcylation enhances etoposide-induced p53-mediated apoptosis in HepG2 human liver cancer cells
Jaehoon Lee, Gi‐Bang Koo, Jihye Park, Byung-Cheol Han, Mijin Kwon, Seung‐Ho Lee
This study shows that reducing O-GlcNAcylation enhances etoposide-induced apoptosis in HepG2 cells via the p53/caspase-3/PARP1 pathway.
FEBS Open Bio · Apr 16, 2025Peer-reviewedMolecular Biology