TB-Bench: A Systematic Benchmark of Machine Learning and Deep Learning Methods for Second-Line TB Drug Resistance Prediction
V P Brintha, Saish Jaiswal, Ansh Meshram, Deepti PVS, Sidharthan S C, Manikandan Narayanan
TB-Bench benchmarks ML and DL models for predicting second-line TB drug resistance using WGS data, finding traditional ML models outperform DL models in internal testing but show comparable performance in external validation.
bioRxiv · Apr 13, 2026 · PreprintBioinformatics