Author

Anna Spinelli

University of ZurichORCID 0000-0002-8829-7405Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Adriano AguzziiD· 2 shared Ashutosh DhingraiD· 2 shared Jiang‐An YiniD· 2 shared Peter HeutinkiD· 2 shared Simone HornemanniD· 2 shared Andra ChincisaniD· 1 shared Andrea ArmaniiD· 1 shared Berre Doğançay· 1 shared

Activity by Year

2021-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersGenomics

Adriano AguzziORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

GenomicsbioRxivPreprintMay 25, 2022

Robust and Versatile Arrayed Libraries for Human Genome-Wide CRISPR Activation, Deletion and Silencing

Jiang‐An Yin, Lukas D. Frick, Manuel C. Scheidmann…·Adriano Aguzzi

The paper constructs genome-wide CRISPR libraries for gene ablation, activation, and silencing with high efficacy and reports novel gene regulators and modifiers.

19 citations

humanCRISPR screen

NeurosciencebioRxivPreprintJan 28, 2021

Novel regulators of PrPC biosynthesis revealed by genome-wide RNA interference

Daniel Heinzer, Merve Avar, Daniel Pease…·Adriano Aguzzi

This paper identifies 54 novel regulators of PrPC expression through a genome-wide RNA interference screen, with 9 confirmed by CRISPR interference, revealing potential therapeutic targets for prion diseases.

3 citations

humanbulk RNA-seq