Author

Jie Lan

Chinese Academy of SciencesORCID 0000-0002-8919-8425Unclaimed ORCID profile · follow to get notified of new preprints

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Jie Lan6 papers · Shandong University

Biology Disciplines

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Bioinformatics· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Approach:deep learning· 1 Research Focus:software / tool· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

Guangtao Song· 1 shared Jizhong LouiD· 1 shared Xiaowen WangiD· 1 shared Yang CuiiD· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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4 top collaborators · 6 mutual co-author links

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1 shared paperBioinformatics

Guangtao Song

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1 paper

Recent·Most cited

BioinformaticsbioRxivPreprintMar 4, 2020

Optimized sgRNA design by deep learning to balance the off-target effects and on-target activity of CRISPR/Cas9

Jie Lan, Yang Cui, Xiaowen Wang…·Jizhong Lou

The paper develops a deep learning-based tool, OPT-sgRNA, to design CRISPR sgRNAs that balance on-target activity and off-target effects using public CRISPR screen data.

DOI 10.1101/2020.03.04.976340

CRISPR screendeep learning