Genetic & Genomic MedicineeLifePeer-reviewed
A common 1.6 Mb Y-chromosomal inversion predisposes to subsequent deletions and severe spermatogenic failure in humans
Pille Hallast, Laura Kibena, Margus Punab…·Maris Laan
The paper identifies a 1.6 Mb Y-chromosomal inversion in the AZFc region as a high-penetrant risk factor for male infertility, increasing the risk of spermatogenic failure by 8.6-fold.
21 citations