Hierarchical Approaches for Integrating Sparse, Multivariate Toxicological Effect Data in Whole Organism Molecular Dynamics Models
Florian Schunck, Wibke Busch, Andreas Focks
The paper uses Bayesian hierarchical ODE models to integrate sparse, multivariate toxicity data from zebrafish embryos, improving parameter estimation despite experimental variability and model inadequacy.
bioRxiv · May 9, 2025 · PreprintBioinformatics