Dysmorphic neuron density underlies intrinsic epileptogenicity of the centre of cortical tubers
Sarah E. M. Stephenson, Harley G. Owens, Kay Richards, Wei Shern Lee, Colleen E. D’Arcy, Sarah Barton, Simone Alyson Mandelstam, Wirginia June Maixner, Duncan P MacGregor, Steven Petrou, Paul J. Lockhart, Anthony Simon Harvey, Richard Jacob Leventer
This study shows that resecting only the center of cortical tubers in TSC patients eliminates seizures without functional deficits, as the center has higher dysmorphic neuron density.
bioRxiv · Jun 10, 2019 · PreprintNeuroscience