Lincong Wang

The solvent-excluded surfaces of water-soluble proteins

The paper analyzes the solvent-excluded surface (SES) of water-soluble proteins to understand its role in solvation, folding, and function, finding that SES has a negative net charge and correlates with solubility and hydrophobicity.

An accurate and robust algorithm for solvent-excluded surface computation

The paper introduces an accurate and robust algorithm for computing solvent-excluded surfaces, enabling large-scale analysis of protein and ligand-protein interaction interfaces.

The quantification of protein-protein interaction interfaces using solvent-excluded surface-defined properties

The paper proposes a new model for protein-protein interaction interfaces based on solvent-excluded surface-defined properties, distinguishing between accessible, buried, and partially-buried atoms.