The limitations of non-mechanistic methods for characterizing pathogen-pathogen interactions: A simulation study
Sarah Krämer, Sarah Pirikahu, Cana Kussmaul, Lulla Opatowski, Matthieu Domenech de Cellès
This paper evaluates non-mechanistic methods for detecting pathogen-pathogen interactions using simulations and finds they often fail to accurately infer interactions or their strength.
PLoS Computational Biology · Aug 17, 2026Peer-reviewedEcology