Helmut Simon

This paper introduces a Bayesian method to infer coalescence times from the site frequency spectrum, applied to simulated and historical mitochondrial data.

This paper introduces a new likelihood-based test for natural selection, called rho, which outperforms Tajima's D in detecting selection signals and adapts to demographic histories and sequencing errors.

The paper quantifies how recombination and sequence context influence human genome mutation rates and finds context effects are significant but overshadowed by base-pair interactions.