Author

Beat Christen

University of StuttgartORCID 0000-0002-9528-3685Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Andreas L. GimpeliD· 1 shared Bowen FaniD· 1 shared Dexiong CheniD· 1 shared Karsten Michael BorgwardtiD· 1 shared Laetitia Meng-PapaxanthosiD· 1 shared Laetitia O. D. WölfleiD· 1 shared Max HorniD· 1 shared Philipp L. AntkowiakiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperMolecular Biology

Andreas L. GimpelORCID

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1 paper

Recent·Most cited

Deep learning uncovers sequence-specific amplification bias in multi-template PCR

Andreas L. Gimpel, Bowen Fan, Dexiong Chen, Laetitia O. D. Wölfle, Max Horn, Laetitia Meng-Papaxanthos, Philipp L. Antkowiak, Wendelin Jan Stark, Beat Christen, Karsten Michael Borgwardt, Robert N. Grass

This study uses 1D-CNNs to predict PCR amplification bias from DNA sequences, identifying self-priming as a previously overlooked mechanism.

bioRxiv · Sep 20, 2024 · PreprintMolecular Biology