Author

Vladimı́r Setnička

University of Chemistry and Technology, PragueORCID 0000-0002-9615-7955Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Bioinformatics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:protein design· 1 Assay:protein sequence· 1 Approach:statistical model· 1

Frequent Co-Authors

Karel Půbal· 1 shared Karolína LoužeckáiD· 1 shared Kseniia Kushnir· 1 shared Petra LipovováiD· 1 shared Vojtěch SpiwokiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperBioinformatics

Karel Půbal

Mutual co-authors in cluster

Author profile →

1 paper

Recent·Most cited

BioinformaticsFEBS JournalPeer-reviewedSep 29, 2026

Toward a Minimal Amino Acid Alphabet for Protein Design

Karel Půbal, Kseniia Kushnir, Vojtěch Spiwok…·Petra Lipovová

The paper designs proteins using reduced amino acid alphabets and shows that 8 amino acids can form stable proteins, while smaller alphabets fail in experimental validation.

DOI 10.1111/febs.70751

protein sequencestatistical model